O-Benzotriazole-N,N,N’,N’-tetramethyl-uronium hexafluorophosphate: A versatile reagent with a variety of applications


O-Benzotriazole-N,N,N’,N’-tetramethyl-uronium hexafluorophosphate, CAS 94790-37-1 also known as HBTU, is a white or colorless solid that is soluble in polar solvents. It is a versatile reagent with a variety of applications, including:

  •  Polymer synthesis: HBTU is used to synthesize polymers, such as polyimides, polyurethanes, and polyamides. It is used in the production of resins, adhesives, and coatings.
  • Chemical intermediate: HBTU is used as a chemical intermediate in the synthesis of a variety of other chemicals, such as pharmaceuticals, pesticides, and cosmetics.
  •  Reagent: HBTU is used as a reagent in a variety of organic reactions, such as the acylation reaction and the activation of amines.
  • Catalyst: HBTU is a catalyst for a variety of reactions, such as the esterification reaction and the amidation reaction.
  •  Solvent: HBTU is used as a solvent for a variety of organic compounds, such as amines, carboxylic acids, and alcohols.

How does HBTU work?

HBTU works as a reagent by reacting with other molecules to form new compounds. It does this by donating its N-hydroxysuccinimide (NHS) group to the molecules it is reacting with. The NHS group is a very reactive group that can react with a variety of functional groups.

Safety precautions

HBTU is a hazardous chemical and should be handled with care. It can be harmful if it comes into contact with skin, eyes, or ingested. HBTU can also be harmful if inhaled.

Here are some safety precautions to take when working with HBTU:

· Wear gloves, goggles, and a lab coat when handling HBTU.

· Work in a well-ventilated area.

· If HBTU comes into contact with skin, wash the area with soap and water immediately.

· If HBTU comes into contact with eyes, flush them with water for 15 minutes and seek medical attention immediately.

· If HBTU is ingested, do not induce vomiting. Call poison control immediately.

HBTU is a versatile reagent with a variety of applications. It is important to handle HBTU with care and to follow all safety precautions.

Here are some additional information about HBTU:

· HBTU is a white or colorless solid.

· HBTU is a hazardous chemical and should be handled with care.

· HBTU is used as a polymer synthesis, chemical intermediate, reagent, catalyst, and solvent.

· HBTU is a strong acid and can cause burns to skin and eyes.

· HBTU is a toxic substance and can be harmful if inhaled or ingested.

· HBTU is a moisture-sensitive compound and should be stored in a dry place.

I hope you find this blog informative.

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